FkTRX-04 for thioredoxin assays.

IMCO has decided that the sensitive fluorescence assay using FITC-insulin will soon be introduced again as FkTRX-04. The advantage is that the wavelengths involved are 480nm for excitation and 520 nm for recording the increase in emission. This may fit some plate readers better than the specification for FkTRX-02-V2 which uses eosin-insulin with excitation at 520 and recording at 545 nm. The contents of the kits are the same except for the fluorescent substrates.

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New kit for high sensitivity GSH measurements

Measuring GSH in plasma and serum requires high sensitivity and is complicated by oxidation in samples upon storage. IMCO has developed a new kit for high sensitivity fluorescent determinations of GSH, GSSG and glutathionylated products.


Mammalian thioredoxin reductases: TR-03 and TR-03B

Mammalian thioredoxin reductase 1 (TrxR) contain an essential seleocycteine residue encoded by the stop codon UGA. This makes recombinant expression in E.coli a challenge. IMCO now has preparations of rat TrxR with unsurpassed specific activity.