Oxidative stress by FkGRX-01
2014.10.09

Oxidative stress results in oxidation of glutathione (GSH). Glutaredoxin ( Grx) uses the reductive power of GSH to reduce oxidized proteins. Grx1 is present in plasma and is a marker of oxidative stress (1). The FkGRX-01 kit measures Grx activity in 20-40 Ál of plasma.
References:
1.Du, Y., Zhang, H., Montano, S., Hegestam, J., Ekberg, N.R., Holmgren, A., Brismar, K. and Ungerstedt, J.S.: Plasma glutaredoxin activity in healty subjects and patients with abnormal glucose levels or overt type 2 diabetes. Acta Diabetol. 51, 225-232, 2014.

FkGRX-01 (pdf, 165 kB)

Tillbaka...




New kit for high sensitivity GSH measurements

Measuring GSH in plasma and serum requires high sensitivity and is complicated by oxidation in samples upon storage. IMCO has developed a new kit for high sensitivity fluorescent determinations of GSH, GSSG and glutathionylated products.

Read more...

Mammalian thioredoxin reductases: TR-03 and TR-03B

Mammalian thioredoxin reductase 1 (TrxR) contain an essential seleocycteine residue encoded by the stop codon UGA. This makes recombinant expression in E.coli a challenge. IMCO now has preparations of rat TrxR with unsurpassed specific activity.

Read more...